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Viagra (Sildenafil citrate), which millions of men take for erectile dysfunction (ED), reduces the effects of hormonal stress on the heart by half, according to a study published online in the journal Circulation. Viagra causes genital blood vessels to expand, which helps in maintaining an erection. Recent research also has pointed to its potential usefulness in treating pulmonary hypertension. Prior to the latest findings by a team of Johns Hopkins researchers, it was thought to have little effect on the heart. Viagra, or sildenafil, blunts the strengthened heart beat caused by chemically induced stress, according to study senior author and cardiologist David Kass, MD, a professor at the Johns Hopkins University School of Medicine and its Heart Institute. It thereby lessens both the excess amount of blood and the force used to pump it to the body. "Sildenafil effectively puts a 'brake' on chemical stimulation of the heart," says Kass. Prevents and Reverses Effects of High BP These findings are believed to be the first confirmation in humans that Viagra has a direct effect on the heart. In earlier research, Kass and his team observed a similar effect in mice; Sildenafil blocked the short-term effects of hormonal stress in the heart. Related studies by the group show that sildenafil also prevents and reverses the long-term effects of chronic high blood pressure on the heart. Sildenafil reversed the negative effects on heart muscle weakened by heart failure and enlargement -- a condition called hypertrophy -- in mouse experiments Kass and his team carried out earlier this year. They reported their results in the journal Nature Medicine. "But we had no firm evidence as to whether or how this therapy might work in the human heart," says Kass. "Our latest research provides firm evidence this drug does indeed have an important impact on the heart." Increased Heartbeat Was Slowed Thirty-five healthy men and women, with an average age of 30 and no previous signs of coronary artery disease, participated in the six-month Johns Hopkins study. Within a three-hour timeframe, each participant received two separate injections of dobutamine (5 micrograms per kilogram for five minutes), a synthetic, adrenaline-like chemical that increases heart rate and pumping strength. Between injections, study participants were assigned randomly to a group that was treated with sildenafil (100 milligrams taken orally) or to a group given a sugar pill placebo. All participants then were given the second dobutamine injection to see what effects sildenafil or placebo had on the heart. Measurements of heart function were made before and after each injection. These included blood pressure readings, electrocardiograms and echocardiograms. Blood samples confirmed relatively equal levels of sildenafil and other enzymes. Each dobutamine injection stimulated heart function, increasing heart rate and the force of each heartbeat used to pump blood throughout the body, results showed. "This stimulation is similar to the way the nervous system normally increases heart function when triggered by emotional or exercise stress, or in diseases such as heart failure," notes Kass. After the first injection of dobutamine, the force of heart contraction increased by 150 percent in both groups. In the placebo group, this increase repeated itself after the second injection. However, in the group treated with sildenafil, the increased heartbeat was slowed by 50 percent, resulting in a smaller increase in blood flow and blood pressure generated by the heart in response to chemical stimulation. Between injections, heart function was not altered in the sildenafil group, demonstrating the absence of adverse side effects on the resting human heart. Stops PDE5A Action "Knowing more about the effects of sildenafil on heart function will allow for safer evaluation of its use as a treatment for heart problems," says Kass. "Our results set the stage for further studies of sildenafil's immediate and long-term effects on the heart and its ability to modify other neurohormonal and stress stimuli, including adrenaline and hypertension," he adds. While the precise biological actions of sildenafil in the heart are not fully understood, the drug is known to work by stopping the action of an enzyme, called phosphodiesterase 5 (PDE5A), Kass explains. This enzyme is involved in the breakdown of a key molecule, cyclic GMP, which helps control stresses and limit overgrowth in the heart. PDE5A is also the biological pathway that sildenafil blocks in the penis to prevent the relaxation of blood vessels and thus maintain erections. Copyright 2005 Daily News Central cheap penis elargement best pnis enlargement surgery enhancement manhattan penis penis enlargment result get vig rx cheapest pnis enlargement pills vimax home penis enlargement penis enlarement without pills

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Testosterone deficiency, also known as hypogonadism, is a condition in which the testes are unable to produce enough testosterone to fulfill the body's needs. Testosterone deficiency has many possible causes, including genetic abnormalities, injury to the testes, and being on certain medications. Normal aging also may play a role in the decline of male testosterone levels. It is also known as low testosterone. The testes produce testosterone regulated by a complex chain of signals that begins in the brain. This chain is called the hypothalamic-pituitary-gonadal axis. The hypothalamus secretes gonadotropin-releasing hormone (GnRH) to the pituitary gland in spurts, which trigger the secretion of leutenizing hormone (LH) from the pituitary gland. This hormone stimulates the Leydig cells of the testes to produce testosterone. Normally, the testes produce 4-7 milligrams (mg) of testosterone each and every day. After puberty, testosterone production increases rapidly, and will decrease rapidly after age 50. Recent estimates show that approximately 13 million men in the United States experience testosterone deficiency and less than 10-percent receive treatment for the condition, which is growing in cultural acceptability. Studies also have shown that some men with obesity, diabetes, or hypertension may be twice as likely to have low testosterone levels, though as stated, low testosterone and testosterone deficiency can be caused by taking certain medications, chemotherapy, infections and other basic causes. Signs of testosterone deficiency depend on the age of onset and the duration of hormonal deficiency. Congenital testosterone deficiency is usually characterized by underdeveloped genitalia, and sometimes even undeterminable genitalia. Acquired testosterone deficiency that develops near puberty can result in enlargement of breast tissue (gynecomastia), sparse or absent pubic and body hair, and underdeveloped penis, testes, and muscle. Adults may experience diminished libido, erectile dysfunction, muscle weakness, hair loss, depression, and other common mood disorders. penile enlargement stretcher penis enlarement pills product manual penile enlargment natural penile enlargement exercise does vimax work penis enhancement excersizes buy place vig rx elargement free penis pills sample real pennis enlargement

Children and teenagers are commonly confronted with strep throat. Due to its very contagious character, strep throat can be easily acquired by children during the flu seasons. Strep throat is a type a sore throat caused by infection with group A streptococcus bacteria. Unlike sore throat, the bacterial form of the illness usually generates more intense symptoms which can persist for more than a week. Strep throat can cause symptoms such as throat inflammation and pain, enlargement of the tonsils and lymph nodes, difficult swallowing, difficult breathing, mucus-producing cough, headache, fatigue, poor appetite, nausea and fever. When it occurs in children, strep throat can also be accompanied by skin rash. The reason why strep throat is very common among children and teenagers is that they interact with large groups of persons in kindergarten or school, rendering them very vulnerable to contracting streptococcus bacteria or other infectious agents. In order to avoid the occurrence of strep throat, it is very important to timely educate your child in maintaining a good level of personal hygiene. Proper personal hygiene is a very effective means of preventing strep throat and many other types of contagious diseases. Especially in the flu seasons, teach your child to wash his hands regularly and to avoid sharing personal items with other people. Once acquired, strep throat can be very difficult to overcome and hence it is best to take proper measures in preventing the occurrence of the illness in the first place. When your child has a persistent sore throat accompanied by fever, inflamed tonsils and lymph nodes, it is a sign of infection with bacteria and you should pay a visit to a pediatrician as soon as possible. Before seeking medical guidance, avoid giving your child left-over medications, as you can generate more harm rather than good. Administered to very young children, even aspirin can have pronounced side-effects. It is very important to note that strep throat doesn’t clear on itself. Unlike most sore throats, strep throat may require a course of antibiotics. Although antibiotics have various side-effects and they also attack the body’s benign bacterial flora, in present they are the best means of curing strep throat. Prescribed in the incipient stages of infection, antibiotics such as penicillin and amoxicillin can effectively overcome strep throat, also minimizing the risk of developing complications. If the infection is serious, the doctor may prescribe a course of cephalosporins, a strong type of antibiotics. In order to ensure a complete recovery and to avoid a recurrence of the infection, the medical treatment with antibiotics needs to be administered for at least 10 days. It is very important to follow the doctor’s exact instructions when giving antibiotics to your child. Make sure that you respect the dosage specified by the doctor and avoid interrupting the treatment prematurely. Even if the child appears to be completely recovered from illness within the first days of treatment, it is important to complete the course of antibiotics in order to minimize the chances of relapse. enhancement manhattan penis vig rx pill penile enlargement tip penile enlargment before and after photo penis enargement surgeon vimax free penis enlargement exercise medical penis enlargement permanent penis enlarement real pennis enlargement

Semen, or cum, is actually made up of ninety percent (90%) seminal fluids including fructose (sugar) and proteins; sperm accounts for only about one percent (1%) of its total volume and the rest is made up of trace minerals and nutrients. Many guys are concerned with what their semen tastes like. This may rise from the fact that they want to score blow jobs. First of all, you can stress to your partner that semen will not make a person fat. It contains only about 12 to 15 calories per ejaculation; the same amount found in gelatin or egg white. Some people say that semen tastes bitter, salty, or even acrid. So for loads of exciting fun in the bedroom, you can make your partner swallow your cum if you make your cum taste better. Since semen is excreted by the body, its taste and smell would most likely be affected by what you eat and drink. What is the best diet for better-tasting cum? For one, you should start living a clean and healthy lifestyle. Say no to alcohol, drugs and nicotine. Avoid junk foods and instead have lots of fruits and greens in your diet. Plus, drink a lot of liquids (water). Drinking fruit juices from pineapple, citrus, and cranberry is also known to make your cum taste sweeter. Throw in melon, mango, apple, or grape, and other fruits that are high in sugar. Likewise, vegetables like parsley and celery are recommended. There are also some foods that you should steer clear of. Fish and red meat produce a bitter, fishy taste because of their alkaline content. Chemically-processed alcohol can also make your semen taste bitter. Instead, try naturally fermented drinks for a change. Garlic and onion are likely to produce strong odors since they are high in sulfur; so lay off on these. A better-tasting semen is good; but having extra loads of better-tasting semen is better. The volume of your load depends upon a number of concerns, including age, heredity, and general health. We practically can't change our age and genetics, but we could instead make dietary adjustments. There are various supplements that you can take like zinc oxide, Horny Goat Weed, L-Arginine, L-Lysine which are supposed to boost quantity of your load. By simply increasing your fluid intake, you can increase the amount of your ejaculation. When your body is well hydrated, your body systems are able to work more efficiently and have less trouble getting water from the bloodstream. Brian Green Source: Penis Enlargement Products does vig rx work free natural penile enlargement pnis enlargement system cheapest penis enlargement pills easy enhancement free penis surgery way penis enlagement tool free pennis enlargement penile enlargment supplement real pennis enlargement