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Viagra (Sildenafil citrate), which millions of men take for erectile dysfunction (ED), reduces the effects of hormonal stress on the heart by half, according to a study published online in the journal Circulation. Viagra causes genital blood vessels to expand, which helps in maintaining an erection. Recent research also has pointed to its potential usefulness in treating pulmonary hypertension. Prior to the latest findings by a team of Johns Hopkins researchers, it was thought to have little effect on the heart. Viagra, or sildenafil, blunts the strengthened heart beat caused by chemically induced stress, according to study senior author and cardiologist David Kass, MD, a professor at the Johns Hopkins University School of Medicine and its Heart Institute. It thereby lessens both the excess amount of blood and the force used to pump it to the body. "Sildenafil effectively puts a 'brake' on chemical stimulation of the heart," says Kass. Prevents and Reverses Effects of High BP These findings are believed to be the first confirmation in humans that Viagra has a direct effect on the heart. In earlier research, Kass and his team observed a similar effect in mice; Sildenafil blocked the short-term effects of hormonal stress in the heart. Related studies by the group show that sildenafil also prevents and reverses the long-term effects of chronic high blood pressure on the heart. Sildenafil reversed the negative effects on heart muscle weakened by heart failure and enlargement -- a condition called hypertrophy -- in mouse experiments Kass and his team carried out earlier this year. They reported their results in the journal Nature Medicine. "But we had no firm evidence as to whether or how this therapy might work in the human heart," says Kass. "Our latest research provides firm evidence this drug does indeed have an important impact on the heart." Increased Heartbeat Was Slowed Thirty-five healthy men and women, with an average age of 30 and no previous signs of coronary artery disease, participated in the six-month Johns Hopkins study. Within a three-hour timeframe, each participant received two separate injections of dobutamine (5 micrograms per kilogram for five minutes), a synthetic, adrenaline-like chemical that increases heart rate and pumping strength. Between injections, study participants were assigned randomly to a group that was treated with sildenafil (100 milligrams taken orally) or to a group given a sugar pill placebo. All participants then were given the second dobutamine injection to see what effects sildenafil or placebo had on the heart. Measurements of heart function were made before and after each injection. These included blood pressure readings, electrocardiograms and echocardiograms. Blood samples confirmed relatively equal levels of sildenafil and other enzymes. Each dobutamine injection stimulated heart function, increasing heart rate and the force of each heartbeat used to pump blood throughout the body, results showed. "This stimulation is similar to the way the nervous system normally increases heart function when triggered by emotional or exercise stress, or in diseases such as heart failure," notes Kass. After the first injection of dobutamine, the force of heart contraction increased by 150 percent in both groups. In the placebo group, this increase repeated itself after the second injection. However, in the group treated with sildenafil, the increased heartbeat was slowed by 50 percent, resulting in a smaller increase in blood flow and blood pressure generated by the heart in response to chemical stimulation. Between injections, heart function was not altered in the sildenafil group, demonstrating the absence of adverse side effects on the resting human heart. Stops PDE5A Action "Knowing more about the effects of sildenafil on heart function will allow for safer evaluation of its use as a treatment for heart problems," says Kass. "Our results set the stage for further studies of sildenafil's immediate and long-term effects on the heart and its ability to modify other neurohormonal and stress stimuli, including adrenaline and hypertension," he adds. While the precise biological actions of sildenafil in the heart are not fully understood, the drug is known to work by stopping the action of an enzyme, called phosphodiesterase 5 (PDE5A), Kass explains. This enzyme is involved in the breakdown of a key molecule, cyclic GMP, which helps control stresses and limit overgrowth in the heart. PDE5A is also the biological pathway that sildenafil blocks in the penis to prevent the relaxation of blood vessels and thus maintain erections. Copyright 2005 Daily News Central magna rx plus herbal penile enlargment pills free natural penis enlarement herbal penis enlarement pills magna rx review home penis enlarement natural penis elargement exercise free penile enlargment pills

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Quick, answer a question: Why do people buy from you? Bzzzzz. Wrong, if you answered with, • “Uhhh . . .” • Any description of your product or service. You get an “Incomplete” if you answered, • “Because we have great service.” • “We have the best quality.” This might seem rather basic to some of you, but if you quit reading I promise you're cheating yourself. Unless you have an inside-and-out understanding of all the possible reasons people buy from you, you're likely inviting objections. That's because you're probably selling what you want to sell, or talking about what the company's marketing department tells you are “benefits.” People buy for their reasons, not yours. Your goal on calls is to learn, remind them of, and understand their reasons for being interested in you, and ultimately buying. An Example Let's look at an example. A copy machine salesperson calls a smaller company, hoping to sell a copier. He speaks with the Office Manager who typically makes decisions like this one. After asking a few basic qualifying questions he learns the office has four people in it, and they now have a big old monster of a copy machine that has been in the office for about eight years. Thinking he has a hot prospect, the rep launches into a pitch about the latest techno-copier that does everything but write the documents for you. He overwhelms the listener with a point-by-point description of each of the “benefits”-or what he thinks are benefits (they indeed are, to some people). The prospect says, “What we have is working just fine now.” He retorts with some rendition of the “feel-felt-found” technique and rams into a brick wall. He writes this one off, and moves to the next. Same pitch, same result. What Went Wrong? So is the rep not skilled at closing? How about overcoming objections? Neither. You could make a case for him not being a skilled questioner, but that might not be fair. The fact is, he doesn't have a clear understanding of why people buy from him-from their perspective, not his. You see, in this case, the Office Manager was a technophobe. She just traded in her IBM Selectric for a computer for gosh sakes! And, she is paying $300 per year, plus a per copy charge for a maintenance contract on her current dinosaur copier-about half of what a new, smaller, more reliable machine would cost to buy! And that's not all. The prospect was really quite interested in the fact that the machine the rep was pitching could do enlargement and reduction. Her's couldn't, and she had to personally go down to the Quick Copy to have them done, and it was a tremendous hassle. But, the rep had already mentioned so many other “benefits” that were actually perceived negatives to the prospect, that she didn't think it would be worth it to talk about that one feature. However, in isolation, it could have sold her. Even if you think you have a clue about why people buy from you, do the following exercise. And do it often, since situations change regularly. Here's an exercise we work on in training seminars. It lays the foundation for everything else we do. 1. Identify all the different levels and types of buyers and influencers for what you sell. Describe them by title and/or function. For example, depending on the organization, you might have an Advertising Director as the buyer. In smaller companies it could be an Office Manager, or maybe even the President. 2. Taking each of these types of people, identify how they're typically evaluated in their job. A Purchasing Manager is evaluated differently than a sales manager-the former on conservation, while the latter on production. Why should we think about this? We all have a desire to survive-at the very least-in our jobs, and most of us want to thrive. Knowing how someone is measured in their environment provides insight to what makes them tick. 3. Regarding your types of product/service, what do they want and need most? Be as specific as possible. Saying, “They want good quality,” doesn't cut it. If you can't see, feel, hear, touch, or taste it, how can you describe it? Good quality manifests itself in the form of “A machine that requires virtually no servicing other than routine maintenance.” 4. Conversely, what do they want to avoid? Again, be specific, descriptive. Don't say “poor service.” Better: “They hate having to wait three hours to get an answer to a basic technical question.” Answering these questions is just a start. After you've compiled your list, then you use the answers to create questions to determine if, indeed, these possible benefits truly are benefits. vig rx for men pro solution pills review surgical penis elargement penis enlargement cream penis enhancement tool penis enlargment before and after picture best enlargment exercise penile cheap penis enlargment pnis enlargement pic

If you want that perfect show dog look in your Shih Tzu you might as well relax to the fact that it involved brushing, brushing, brushing, and daily brushing. A thorough head-to-tail groom is often needed at least every other day if not “daily.” However, Shih Tzu coat textures are very different. You might get by with once weekly brushing if the Shih Tzu’s coat is the type of texture that does not mat and tangle easily. If you have only one Shih Tzu, grooming should not be a problem. It can be quite pleasurable for you and your Shih Tzu. It can be an excellent time to bond with each other, and have nice close little chats with each other. Where do you start? A good place to start grooming your Shih Tzu is on the tummy, the chest and inside the legs…….perhaps……there are other opinions of course, but in this article I will direct you to start with the tummy, the chest and inside the legs. You will need to have your Shih Tzu lie on his side on the table (be sure you have a nice, sturdy table to groom your Shih Tzu). There is nothing worse than a grooming table that wobbles around, except of course a grooming area that is not organized. You also need to have all your equipment organized and ready to use. So now that you have your Shih Tzu lying on its side on the table, with his legs towards you (this can be an accomplishment in itself that may take several short training sessions to get done). If the Shih Tzu just will not cooperate with you, you can start trying to train him by having him lay tummy upwards in your lap with his head facing your chest. Do this exercise first for a few days if he absolutely refuses to lie this way on the grooming table. If the above fails, you might try to groom the chest and tummy while the Shih Tzu sits on the table facing you, holding him up into a begging position by the front paws; this is not easy, since both hands are needed for some parts of the grooming, but you might have to try this as a last resort. If your Shih Tzu mats the tummy will be a prime target for matting. The tummy side of a Shih Tzu is sensitive also, so be gentle in this area. Check where the legs meet the body, this is a prime target area for severe matting as well. Something you don’t want to deal with is severe mats in these areas. These are extra sensitive areas on your Shih Tzu. The best rule to follow is pay close attention to these areas on a daily basis and never allows the mats to occur. The hair around the male penis can also be a very sensitive trouble spot. It is best to keep this area clean and shaved off. Your male Shih Tzu will give you a sigh of relief when you remove the hair in this area. How do you remove knots and mats? If you come across a mat or knot first try to tease it apart with your fingers. Then take a comb and use the end with coarse teeth to tease out the tangle slowly, working from the outside inwards and holding the hair between the knot and the body between your fingers so that you don’t pull too hard and hurt the Shih Tzu. If all else fails, a knot may have to be cut out. Cut into the knotted hair away from the dog several times before gently using the comb to clear away the knot. Never cut across the coat. This will leave an obvious hole. If you will cut down through the length of the coat you will cause much less damage. Note: The hair on the legs is more likely to tangle than anywhere else. So…..pay particular attention to these areas as well to avoid those awful and painful mats. This article continues in Part II of “Life with the Shih Tzu.” This article is FREE to publish with the resource box. penile enlargement tip enlagement erection penis pill vimax buy penis enlagement pills penis enhancement surgery photo vig rx penis pill best penis enlargment pills cheap penile enlargment herbal natural penile enlargement pnis enlargement pic

Nearly every person feels at least a little bit insecure about certain aspects of himself or herself; it could be looks, height, skin color, and many other things. For many men, their penis size is one thing they wish they could change. There are theories about how this feeling of discontent probably started when they began comparing what they had with what other boys in the locker room had. Maybe some men blame an unsatisfactory sex life on what they think is an inadequate penis. Whatever the reason, many men believe that they fall short of the normal penis size and this affects how they think and feel about themselves in a lot of ways. The prevalent mindset is that bigger is better, and many women feel this way about their bodies, too. How many women have had breast implants done on them because they feel they will look more womanly and more attractive? For men, the perception is that the size of the penis is an indicator of masculinity -- if it’s bigger, he is more macho and someone who should command more respect. It doesn’t help that well-endowed men in porn movies are portrayed as having normal penis size. Also, no matter how much women deny that penis size is unimportant in lovemaking, men will still believe that they will be better lovers if they have big dicks. That’s why it is very important for men to know and understand the facts about normal penis size and to accept the fact that they are indeed normal. According to studies such as the Kinsey report, normal penis size in its flaccid state ranges from 2.5 to 4.5 inches and four to eight inches in the erect state. Interestingly, some penises grow to be much larger when erect, while others barely increase in size. Evidently, how big or small a flaccid penis is does not indicate how large it will be during erection. Another interesting factor that might influence how men see their penises is the viewing angle or perspective. Looking down at it might make it seem smaller than it actually is. That’s why when you compare the size of your dick with those of the other guys in the locker room, yours will usually seem to come up shorter. Insecurity about penis size is also prevalent among teenagers. This is understandable since a lot of adolescents feel the need to be looked up to or at least stand out. Getting laughed at for having a small dick during high school can be a humiliating experience. However, it is worth remembering that the body is still growing at that stage. Some men may reach normal penis size at an earlier age, while others are late bloomers and may attain their maximum growth at a later period. The average man usually has a normal penis size. However, wanting to look and feel better is not at all unusual. If you’re a man who wants to increase your penis size, there are several ways you can go about it. You can try various penis enlargement products that are out on the market, such as penis pumps, traction devices, penis enlargement surgery or phalloplasty, and dietary supplements. It would be wise to seek the advice of experts before you go for any major procedures. For some men, getting psychosexual advice from a psychologist or psychiatrist has helped resolve negative feelings about themselves. Wanting to look good and feel great is entirely normal, but obsessing over it is not. Accepting what nature endowed you with and knowing how to use it is key to self-acceptance -– you may be “normal,” but you are then in no way just “average.” vimax penis enlargement patch best enargement exercise penis penile enlargment pills review erection penis pills size vimax pnis enlargement device free natural penis elargement does penis enlargment work pnis enlargement traction device pnis enlargement pic

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